April 2017 ARTICLE LIST >>
PharmaTutor (April - 2017)
ISSN: 2347 - 7881
(Volume 5, Issue 4)
Received On: 18/12/2016; Accepted On: 10/01/2017; Published On: 01/04/2017
AUTHORS:
Srinivas college of pharmacy,
Mangalore, Karnataka India,
nayak.pranav10@gmail.com
ABSTRACT:
Cinnamon is used as a spice in our day to day life. It is aromatic. It is principally employed in cookery as a condiment and flavoring agent. It has been acquainted as one of the healthiest spices and has medicinal activity. When it is checked for chemical constituents it reveals phenolic flavonoid and carotenoid contents. They contain rich amount of polyphenols which are powerful antioxidants. It inhibits the growth of certain bacteria and fungi. It helps to reduce the blood glucose by increasing insulin in the body by the mechanism of resisting insulin depletion. It interferes with carbohydrate digesting enzyme and reduces degradation of carbohydrate as a result of which it decreases entry of glucose from intestine to blood stream.
How to cite this article: Nayak P;Cinnamon: A Magical Drug; PharmaTutor; 2017; 5(4);38-41
[ABSTRACT WITH CITATION] [VIEW AS HTML]
REFERENCES:
1. Park EJ, Pezzutto JM. Botanicals in cancer chemoprevention.Cancer and Metastasis Reviews. 2002; 21: 231-55.
2. Senanayake UM, Lee TH, Wills RBH. Volatile constituents of cinnamon (Cinnamomum zeylanicum) oils.Journal of Agricultural and Food Chemistry. 1978;26(4):822¬4.
3. Singh G, Maurya S, de Lampasona MP, Catalan CAN. A comparison of chemical, antioxidant and antimicrobial studies of cinnamon leaf and bark volatile oils, oleoresins and their constituents. Food and Chemical Toxicology. 2007;45(9):1650¬61.
4. Tung YT, Yen PL, Lin CY, Chang ST. Antiinflammatory activities of essential oils and their constituents from different provenances of indigenous cinnamon (Cinnamomum osmophloeum) leaves. Pharmaceutical Biology. 2010;48(10):1130¬6.
5. Unlu M, Ergene E, Unlu GV, Zeytinoglu HS, Vural N. Composition, antimicrobial activity and in vitro cytotoxicity of essential oil from Cinnamomum zeylanicum Blume (Lauraceae).Food Chem Toxicol. 2010;48(11):3274¬80.
6. Cao H, Polansky MM, Anderson RA. Cinnamon extract and polyphenols affect the expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3T3¬L1 adipocytes. Archives of Biochemistry and Biophysics. 2007;459(2):214¬22.
7. Li HB, Wong CC, Cheng KW, Chen F. Antioxidant properties in vitro and total phenolic contents in methanol extracts from medicinal plants. LWT¬Food Science and Technology. 2008;41(3):385¬90.
8. Yang CH, Li RX, Chuang LY. Antioxidant activity of various parts of Cinnamomum cassia extracted with different extraction methods. Molecules. 2012;17(6):7294¬304.
9. Hili P, Evans CS, Veness RG. Antimicrobial action of essential oils: the effect of dimethylsulphoxide on the activity of cinnamon oil. Letters in Applied Microbiology. 1997;24(4):269¬75.
10. Prabuseenivasan S, Jayakumar M, Ignacimuthu S. In vitro antibacterial activity of some plant essential oils.BMC Complementary and Alternative Medicine. 2006;6: 39.
11. Matan N, Rimkeeree H, Mawson AJ, Chompreeda P, Haruthaithanasan V, Parker M. Antimicrobial activity of cinnamon and clove oils under modified atmosphere conditions. International Journal of Food Microbiology. 2006;107(2):180¬5.
12. Gende L, Floris I, Fritz R, Eguaras MJ. Antimicrobial activity of cinnamon (Cinnamomum zeylanicum) essential oil and its main components against paenibacillus larvae from argentine.Bulletin of Insectology. 2008;61(1):1¬4.
13. Goni P, L´opez P, S´anchez C, G´omez¬Lus R, Becerril R, Ner´ın C. Antimicrobial activity in the vapour phase of a combination of cinnamon and clove essential oils.Food Chemistry. 2009;116(4):982¬9.
14. Parthasarathy H, Thombare S. Evaluation of antimicrobial activity of Azadirachta indica, Syzygium aromaticum and Cinnamomum zeyalnicum against oral microflora.Asian Journal of Experimental Sciences. 2013;27(2):13¬16.
15. Varalakshmi B, Vijaya AA, Karpagam T, Suguna Bai J, Manikandan R. In vitro antimicrobial and anticancer activity of Cinnamomum zeylanicum Linn bark extracts. Int J Pharm Pharm Sci. 2013;6(1):12¬18.
16. Khan A, Bryden NA, Polansky MM, Anderson RA. Insulin potentiating factor and chromium content of selected foods and spices. Biological Trace Element Research. 1990;24(3):183¬8.
17. Broadhurst CL, Polansky MM, Anderson RA. Insulin like biological activity of culinary and medicinal plant aqueous extracts in vitro.Journal of Agricultural and Food Chemistry. 2000;48(3):849¬52.
18. Jarvill¬Taylor KJ, Anderson RA, Graves DJ. A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3¬L1 adipocytes. Journal of the American College of Nutrition. 2001;20(4):327¬36.
19. Kim SH, Hyun SH, Choung SY. Anti¬diabetic effect of cinnamon extract on blood glucose in db/db mice. Journal of Ethnopharmacology. 2006;104(1¬2):119¬23.
20. Kreydiyyeh SI, Usta J, Copti R. Effect of cinnamon, clove and some of their constituents on the Na+ ¬K+ -ATPase activity and alanine absorption in the rat jejunum. Food and Chemical Toxicology. 2000;38(9):755¬62.
21. Davis PA, Yokoyama W. Cinnamon intake lowers fasting blood glucose: metaanalysis. J Med Food. 2011;14(9):884¬9.
22. Hoehn AN, Stockert AL. The Effects of Cinnamomum Cassia on Blood Glucose Values are Greater than those of Dietary Changes Alone. Nutr Metab Insights. 2012;5:77-¬83.
23. Lu T, Sheng H, Wu J, Cheng Y, Zhu J, Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408¬12.
24. Akilen R, Pimlott Z, Tsiami A, Robinson N. Effect of short¬term administration of cinnamon on blood pressure in patients with prediabetes and type 2 diabetes. Nutrition. 2013;29(10):1192¬6.
25. Sheng X, Zhang Y, Gong Z, Huang C, Zang YQ. Improved Insulin Resistance and lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator¬Activated Receptors. PPAR Res. 2008;581348.
26. Absalan A, Mohiti¬Ardakani J, Hadinedoushan H, Khalili MA. Hydro¬Alcoholic Cinnamon Extract, Enhances Glucose Transporter Isotype¬4 Translocation from Intracellular Compartments into the Cytoplasmic Membrane of C2C12 Myotubes. Indian J Clin Biochem. 2012;27(4):351¬6.
27. Jiao L, Zhang X, Huang L, Gong H, Cheng B, Sun Y, et al. Proanthocyanidins are the major anti¬diabetic components of cinnamon water extract. Food Chem Toxicol. 2013;56:398¬-405.
28. Lee SC, Xu WX, Lin LY, Yang JJ, Liu CT. Chemical composition and hypoglycemic and pancreas¬protective effect of leaf essential oil fromindigenous cinnamon (Cinnamomum osmophloeum Kanehira). Journal of Agricultural and Food Chemistry. 2013;61(20):490-5¬13.
29. Peng X, Cheng KW, Ma J, Chen B, Ho CT, Lo C, et al. Cinnamon bark proanthocyanidins as reactive carbonyl scavengers to prevent the formation of advanced glycation endproducts. J Agric Food Chem. 2008;56(6):1907-11.
.png)
