The Institute of Life Sciences was conceived in the context of globalization, to foster research competence in India and to bridge the divide between academic research and the pharmaceutical & biotechnology industries. The institute was incorporated as a non-profit entity under Section 25 of the Indian companies act, facilitating operational autonomy. Construction of the ILS building comprising 44 labs and an administrative block and spanning -130,000 sq.ft. in area, began in 2004 and was completed in January 2007. The institute was inaugurated as a public-private partnership research institute on 29th January 2007, a culmination of the efforts and initiative of the Andhra Pradesh state government, Dr. Reddy's laboratories and the University of Hyderabad.

Post : Junior Research Fellows

Project Title: Use of DNAzymes to improve CRISPR-mediated knock-in.

Funding Agency: DBT (Genome Engineering Technologies)

Qualification
• Graduate Degree in Professional Course with NET qualification
• Post Graduate Degree in Basic Science with NET qualification
• Post Graduate Degree in Professional Course
Acceptable NETs: CSIR-NET including LS; GATE, JAM, GPAT, BET, JEST, JGEEBILS, ICMR-JRF and ICAR- AICE.

Candidates with a keen interest in targeted gene modification and prior hands-on experience with molecular biology and cell culture are preferred. Experience with CRISPR would be an additional advantage. A possibility of Ph.D. enrolment exists, but is not guaranteed. Work will involve DNAzyme construction, DNAzyme library creation and verification, recombinant protein purification, CRISPR reagent construction including gRNA design, in vitro transcription, and extensive mammalian cell culture, transfection, and screening including analysis of viability and marker expression.

Project duration: Three years
Appointment will be renewed yearly based on performance

Emoluments
Rs. 25000+HRA per month

APPLICATION DEADLINE: Oct 19, 2018;
INTERVIEW DATE: Oct 24, 2018.
TENTATIVE START DATE: Nov 1, 2018.

Qualified and interested candidates may send their curriculum vitae by e-mail to hr@drils.org on or before the deadline. Mention the following code in the email subject line: CRISPR - Biology. Selected candidates will be called for a personal interview to Dr. Reddy’s Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad. Candidates will not be reimbursed for Travel for the Interview, if shortlisted.

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