A STUDY ON IDENTIFICATION OF RISK FACTORS IN DEVELOPING POLY CYSTIC OVARIAN SYNDROME AMONG TEENAGERS AND MINIMIZING THEM BY LIFE STYLE MODIFICATIONS THROUGH ADVANCED PATIENT COUNSELLING BY DOCTOR OF PHARMACY

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ABOUT AUTHORS
Dr. M. Manasa Rekha1*, Dr.M.Manasa², C.Reddy Kumari^2
1*,² Doctor of pharmacy, Department of Pharmacy Practice,
Annamacharya college of Pharmacy,
Rajampet, Kadapa, Andhra Pradesh, India.
*manasarekharoyal@gmail.com

ABSTRACT:
Poly-Cystic Ovary Syndrome (PCOS) is characterized by multiple small ovarian cysts, obesity, hypertension, diabetes, insulin resistance, and Hirsutism. The Study Aims to assess the role of Doctor Of Pharmacy in identification of risk factors in developing poly cystic ovarian syndrome among teenagers and minimizing them by life style modifications through advanced Patient counseling.The Main Objective of the present study is to prevent the following: To prevent the complications of PCOS who are suffering with PCOS in early of their age. To prevent the occurrence of PCOS to early females who are nearer for its occurrence. To minimize the symptoms and to improve the quality of life of females suffering with PCOS. Study Design: It is a observational and interventional study. Study Period: The Present study was conducted for a period of 6 months from January 2nd  2017 to July 31st 2017.Study site : The Present study was conducted in BAHUDHA WOMENS HOSTEL affiliated to Annamacharya college of Pharmacy, Rajampet, Kadapa, Andhra Pradesh, India. In The Present Study Out of total 600 women   530 enrolled to participate in the present study. After the collection of information by PCOS  self assessment forms the scoring is given as 271 with scoring >5 with percentile 51.1320 are with Chance for getting PCOS, 159 with scoring > 10with percentile 30.01 are with high Chance for getting PCOS, 100 with scoring  <5with percentile 18.8679 are Unpredictable to PCOS. The present study concludes that Doctor Of Pharmacy is very helpful in assessing the risk factors responsible in developing PCOS and also minimizing them by life style modifications through advanced patient counseling.

Reference Id: PHARMATUTOR-ART-2558

INTRODUCTION:
DEFINITION:
Poly-Cystic Ovary Syndrome (PCOS) is characterized by multiple small ovarian cysts, obesity, hypertension, diabetes, insulin resistance, and Hirsutism.

SEQUENTIAL DIAGRAMATIC REPRESENTATION ETIO-PATHOPHYSIOLOGY  OF PCOS:

DIAGRAMATIC REPRESENTATION OF SIGNS AND SYMPTOMS:

COMPLICATIONS:
• Complete Infertility or in some cases difficulty to conceive.
• Cardiovascular diseases like hypertension ,atherosclerosis and other heart problems
• Type-2 diabetes mellitus.
• Hirustism which leads to unusual hair growth on body.
• Hormonal imabalances which leads to endocrine disorders and hyper-androgenism, etc.,,

ROLE OF DOCTOR OF PHARMACY IN MINIMIZING THE RISK FACTORS IN GETTING PCO:
Doctor of pharmacy are health care professionals with complete knowledge on both disease/dicorder and treatment involved as well as on patient counselling and non pharmacological therapy that is helpful to prevent or reduce the complications of a particular disease/disorder, here in this study as a doctor of pharmacy student I have taken a study to control /to reduce/prevent the complications of PCOS in my hostel where I have been 5 years of my study.

METHODOLOGY:
AIM:
The Study Aims to assess the role of Doctor Of Pharmacy in identification of risk factors in developing poly cystic ovarian syndrome among teenagers and minimizing them by life style modifications through advanced  Patient counseling.

OBJECTIVES:
 The Main Objective of the present study is to prevent the following:
• To prevent the complications of PCOS who are suffering with PCOS in early of their age.
• To prevent the occurrence of PCOS to early females who are nearer for its occurrence.
• To minimize the symptoms and to improve the quality of life of females suffering with PCOS.

METHODOLOGY:
Study Design: It is a observational and interventional study.
Study Period: The Present study was conducted for a period of 6 months from January 2nd  2017 to July 31st 2017.
Study site : The Present study was conducted in   BAHUDHA WOMENS HOSTEL affiliated to Annamacharya college of Pharmacy, Rajampet, Kadapa, Andhra Pradesh, India.
Sample size: 600 women with age group ranging from 18-24 were selected for this study.
Source of Data: All the required data was collected through risk factors assessment forms.

PCOS SELF ASSESMENT FORM:

Inclusion criteria:
Females aging between 18-24 and who are willing to participate in the study. ,(Out of total 600   530 were willing to participate in the present study).
Exclusion criteria:
Females aging between 18-24 and who are not willing to participate in the study,(Out of total 600   70 were not willing to participate in the present study).

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RESULTS:
Table1.1 AGE WISE DISTRIBUTION OF FEMALE POPULATION IN BAHUDHA HOSTEL.

Fig 1.1 DIAGRAMATIC REPRESENTATION OF AGE WISE DISTRIBUTION OF FEMALE POPULATION IN BAHUDHA HOSTEL.

Table1. ANALYSIS OF PCOS STATE IN FEMALE POPULATION OF BAHUDHA HOSTEL BY BASED ON SCORING.

Fig 1.2 DIAGRAMATIC REPRESENTATION OF ANALYSIS OF PCOS STATE IN FEMALE POPULATION OF BAHUDHA HOSTEL BY BASED ON SCORING.

PATIENT COUNSELLING TIPS ALONG WITH LIFE STYLE MODIFICATIONS PROVIDED BY DOCTOR OF PHARMACY TO FEMALE POPULATION WHO ARE AT CHANCE AND RISK OF GETTING PCOS:

occurance.
• Always reduce the intake of carbohydrate which can help to regulate menstrual cycles in regular manner.
• Always reduce the intake of  fats with very low density lipoproteins that can helps to weight gain ultimately leads to insulin resistance.
• Always perform regular exercise& yoga to minimize the complications of PCO.
• Always should maintain proper BMI (body mass index).
• Use CARICA PAPAYA before one week of your menstruation date that can help to stimulate the growth of female Harmones like Oestrogen that will help to maintain proper menstruation cycles.
• Diet rich in iron like dates and fibre rich contents along with fruits and fresh vegetables must be taken .
• A balanced diet must be taken by based on body weight for example plate model meal.
• If one found if the complications are heavy they should immediately consult a Gynaecologist.

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HOW DOCTOR OF PHARMACY IS HELPFUL IN ASSESING PCO?
Doctor of pharmacy are health care professionals with deep knowledge in assesing the risk factors, disease status, complications, drug selection, patient counseling. Here in this study a separate self assessment form is produced by doctor of pharmacy professionals as per standard guidelines of W.H.O and other international authorized guidelines, which is helpful for individuals to asses PCO on their own.

DISCUSSION:
In The Present Study Out of total 600 women   530 enrolled to participate in the present study. Among them 95 were under the age group of 18 with percentile 17.9245, 89 were under the age group of 19 with percentile16.7924, 87 were under the age group of 20 with percentile 16.4150, 60 were under the age group of 21with percentile11.3207,  and 40 were under the age group of 22 with percentile 7.5471, 70 were under the age group of 23with percentile 13.2075, 89 were under the age group of 24 with percentile 16.7924. After the collection of information by PCOS  self assessment forms the scoring is given as 271 with scoring >5 with percentile 51.1320 are with Chance for getting PCOS, 159 with scoring > 10with percentile 30.01 are with high Chance for getting PCOS, 100 with scoring  <5with percentile 18.8679 are Unpredictable to PCOS.

CONCLUSION:
The present study concludes that PCOS occurrence is more in teenager females  which can serves as major hurdle for their healthy life which ultimately leads to infertility as it is due to major risk factors like  changes in the diet, stressful life, and  unbalanced improper and unhealthy life style  in females, hence the present study concludes that Doctor Of Pharmacy is very helpful in assessing the risk factors responsible in developing PCOS and also minimizing them by life style modifications through advanced patient counseling.

REFERENCES:
1.A text book of pathophysiology by Harsha Mohan.
2.A text book on pharmaco-therapeutics by Dipirio.
3.American College of Clinical Pharmacy Board of Regents on April 8, 2005.  13000 West      87th Street Parkway, Suite100, Lenexa, KS 66215-4530; e-mail: accp@accp.com, or download from http://www.accp.com.
4.American College of Clinical Pharmacy. Pharmacotherapy 2008-28 (6), 816–817.
5.American College of Clinical Pharmacy.The Definition of Clinical Pharmacy. Pharmacotherapy 2008; 28(6):816-817.
6.Comprehensive pharmacy review by Leon shargel.
7.M. Manasa rekha ,A. Bharath kumar ---a prospective study on implementation of clinical pharmacy services to general medicine department in a teritary care teaching hospital  published in journal of pharma research in ISSN: 2319-5622.
8.Roberts MS , Stokes JA , King MA, Lynne TA, Purdie DM.Outcomes of a randomized controlled trial of a clinical pharmacy intervention in 52 nursing homes. Br J Clin Pharmacol 2001; 51:257-265.
9.Text book Appleton and Langerhan Review Of Pharmacy.
10.Text book named Davidson principles and practice of medicine.
11.W.H.O guidelines how to asses PCO.

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