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March 2017

 

 

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Clinical research courses

The NPPA drug price regulator has reduced the prices of anticancer drugs by almost 86% since last March to relieve patients. There has been "a significant reduction in the prices of cancer drugs since March 2016," said the National Pharmaceutical Pricing Authority (NPPA) in a tweet.

The results of the recent Family Health Survey (NFHS 4) reveal that more than 58 percent of children under five are anemic, ie they suffer from hemoglobin deficiency Blood , Leaving them exhausted, vulnerable to infections, and possibly affecting their development.

According to the World Health Organization, high levels of these markers are clear indications of poor socio-economic conditions and suboptimal health and / or nutritional conditions. In short, lack of food, unhealthy living conditions and poor health care delivery systems.

According to 2011 census data, the total number of children under five in India in 2015 is estimated at 12.4 crore. Thus, about 7.2 crore children are anemic, nearly 5 crore are stunted, about 2.6 crore are wasted and 4.4 crore are underweight. These figures are not too different from those for 2005-2006. Since the population has grown, their share is down.

The survey, which was conducted in 2015-16 and covered six lakh households, also showed that about 38% of children in the same age group were stunted, 21% were wasted and 36% were underweight. Although all internationally accepted markers of child health have improved since the last survey in 2005-2006, levels of undernutrition, mainly caused by poverty, are still high and improvement is too slow.


The survey also found that just over half of all pregnant women were anemic. This automatically translates into their newborn being low. Overall, 53% of women and 23% of men aged 15-49 were anemic.

There are wide variations between states. UP data has not been published due to ongoing surveys, according to Balram Paswan, a professor at the International Institute of Population Sciences in Mumbai, which was the nodal agency for the ministry's survey Of Health. But poorer states like Bihar, Madhya Pradesh, Jharkhand, Assam, Rajasthan and Chhattisgarh have rates above the national average rates on all markers. In Tamil Nadu, 51% of children are anemic while in Kerala, it is more than a third. In many states, stunting has decreased, but the proportion of severely wasted children has increased.


The more advanced states such as those in the south, Haryana and Gujarat have slightly better numbers, but are still at unacceptably high levels. These are clear signs of an endemic hunger crisis in the country that policy makers do not seem to address.

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DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF MECLIZINE AND FOLIC ACID IN BULK AND PHARMACEUTICAL DOSAGE FORMS

{ DOWNLOAD AS PDF }

ABOUT AUHTORS
Naveen Kumar G.S* 1, U. Srinivas 2, Hanumanthchar Joshi 3,
1 Department of Pharmaceutical Analysis,
Sarada Vilas College of pharmacy,
Mysuru, Karnataka, India
2 Department of Pharmacognosy,
Srinivas College of pharmacy, Mangalore, Karnataka India,
3 Department Pharmacognosy,
Sarada Vilas College of pharmacy, Mysuru, Karnataka India
*premukhoja@gmail.com

ABSTRACT  
An UV spectrophotometric method using simultaneous equation was developed for the simultaneous determination of meclizine and folic acid in a binary mixture. In the proposed method, the signals were measured at 390.0 nm and 237.0 nm corresponding to absorbance maxima of and folic acid in methanol respectively. Linearity range was observed in the concentration range of 2-12 µg/ml for both the drugs. Concentration of each drug was obtained by using the absorptivity values calculated for both drugs at two wavelengths, 390.0 nm and 237.0 nm and solving the simultaneous equation. The method was validated and proposed method was fast, accurate and precise so it can be used for regular quality control of the drug.

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