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14 October 2016

Explain the significance of magnitude of “J” constant in structure elucidations.

Q.3. (b) Explain the significance of magnitude of “J” constant in structure elucidations.
Ans.3. (b) Coupling constant: The distance between the centers of the two adjacent peaks in a multiplet is usually constant and is usually called the coupling constant. The value of the coupling constant is independent of the external field. It is measured in Hertz (Hz) or in cps (cycles per second). It is denoted by the letter J.

14 October 2016

Illustrate the following with suitable examples

Q.3. (a) Illustrate the following with suitable examples
(i)Diamagnetic anisotropy
(ii)Correlation Spectroscopy and its significance
Ans.3. (a)
(i). Diamagnetic Anisotropy: Diamagnetic anisotropy is the shielding and deshielding depending on the orientation of the molecule with respect to the applied magnetic field.
Anisotropy is the property of a molecule in different orientations which show variations in physical properties along different axes of the molecule.

14 October 2016

Discuss briefly the theory of ESR spectroscopy

Q.3. (a) Discuss briefly the theory of ESR spectroscopy, spin-spin splitting and its qualitative applications
Ans.3. (a) Electron Spin Resonance It is a branch of absorption spectroscopy in which radiation having frequency in the microwave region is absorbed by paramagnetic substances to induce transitions between magnetic energy levels of electrons with unpaired spins. The magnetic energy splitting is done by applying a static magnetic field.

Read more about Show how you would distinguish between the following by spectroscopy

Q.2. (b) Show how you would distinguish between the following by spectroscopy
     (i) Aldehyde and Ketone
     (ii) Alcohol and Ether
     (iii) Mono substituted benzene and Di-substituted benzene

14 October 2016

Explain ATR phenomenon and its applications

(a) Explain ATR phenomenon and its applications
Ans.2.(a) ATRInternal reflection spectroscopy is a technique for obtaining IR spectra of samples that are difficult to deal with, such as solids of limited solubility, films, threads, pastes, adhesives, and powders. Principle when a beam of radiation passes from a denser to a less dense medium, reflection occurs. The fraction of the incident beam reflected increases as the angle of incidence becomes larger; beyond a certain critical angle, reflection is complete. It has been shown both theoretically and experimentally that during the reflection process the beam penetrate a small distance into the less dense medium before reflection occurs.

14 October 2016

BASICS OF AGING THEORIES AND DISEASE RELATED AGING - AN OVERVIEW

{ DOWNLOAD AS PDF }

ABOUT AUHTORS
Abhijit De*, Chandan Ghosh
Department of Pharmaceutical Science,
Bengal School of Technology, Sugandha,
Hooghly, West Bengal, India
* abhi8981@gmail.com

ABSTRACT
Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. In this review, several theories and mechanisms have been put to explain the molecular basis of aging. For example, random damage of the DNA of somatic cell is believed to accumulate with increasing age. Free radicals produced during oxidation of metabolites for energy production also damage DNA and proteins.

13 October 2016

Career for M.Pharm as Consultant (05 posts) in Department of Public Relation - Govt Jobs | Salary up to 45,000/-

MP, in its present form, came into existence on November 1,2000 following its bifurcation to create a new state of Chhattisgarh.The undivided Madhya Pradesh was founded on November 1, 1956.Madhya Pradesh, because of its central location in India, has remained a crucible of historical currents from North, South, East and West.

Under NHM Madhya Pradesh invites applications from eligible candidates for filling up the following posts on contractual basis in Madhya Pradesh as indicated below.

13 October 2016

Applications are invited for one Junior Research Fellow in A. R. College of Pharmacy

Applications are invited for one Junior Research Fellow (JRF) in a SERB sponsored research project entitled ‘Nasoadhesive nanoemulsion in treatment of Alzheimer disease: Preliminary brain targeting study’ File no: EMR/2016/0000509.

Post : Junior Research Fellow

13 October 2016

Opportunity for Safety Associate at Quintiles | walk in

Quintiles is the only fully integrated biopharmaceutical services company offering clinical, commercial, consulting and capital solutions worldwide. Our network of 23,000 engaged professionals in 60 countries around the globe works with an unwavering commitment to patients, safety and ethics — ensuring a higher level o f healthcare for people. For our biopharmaceutical customers, we help them navigate risk and seize opportunities in an environment where change is constant.

13 October 2016

Novartis looking for Associate Scientist

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Post: Associate Scientist

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October 2016

Explain the significance of magnitude of “J” constant in structure elucidations.

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