September 2016

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ABOUT AUHTORS
MNL Aishwarya, E. Anka Rao, M. Niranjan Babu
Department of Pharmaceutics
Seven Hills College of Pharmacy, Tirupati, AP, India
meenumakkhan@gmail.com

ABSTRACT
Esomeprazole is a proton pump inhibitor used to treat gastric problems mainly peptic ulcers. Peptic ulcers are present in around 4% of the population. They newly began in around 53 million people in 2013. About 10% of people develop a peptic ulcer at some point in their life.They resulted in 301,000 deaths in 2013 down from 327,000 deaths in 1990. The first description of a perforated peptic ulcer was in 1670 in Princess Henrietta of England. H. pylori was first identified as causing peptic ulcers by Barry Marshall and Robin Warren in the late 20th century, a discovery for which they received the Nobel Prize in 2005. Esomeprazole comes under non-surgical treatment for peptic ulcers. Though it is an effective drug used for the treatment of peptic ulcers it includes some side effects such as headache, nausea, diarrhea, decreased appetite…etc., optical isomer of omeprazole is called as s-isomer of omeprazole or esomeprazole which is an improved form of omeprazole. Esomeprazole in combination with cardiovascular drugs produces potential interactions and positive effects. This review article provides an evaluation of the literature on the concomitant use of esomeprazole available. The efficacy, safety, tolerability, cost effectiveness, and patient quality of life of this regimen is discussed. A summary of the pharmacokinetic and pharmacodynamic interactions of esomeprazole, Mechanism of action of omeprazole, as well as its effects during pregnancy are also reviewed.

IIHMR University, Jaipur, is organizing its Annual conference on “SMART Healthcare for India” which will provide a platform for deliberation and discussion on these important issues. Our aim is to bring together leading healthcare and hospital administrators, medical practitioners, healthcare researchers, care-providers, healthcare/hospital/pharmaceutical management/rural management students and policy makers to share cutting-edge research experiences, convey new ideas, debate issues and address latest developments in the domain of healthcare management. In accordance with the theme of the conference, following topics will be discussed by eminent speakers from the academia and industry

ARCI is looking to engage Knowledge Officers and other Personnel at different levels on “Contract Basis” to work on a major time‐bound project entitled “Centre for Knowledge Management of Nanoscience& Technology (CKMNT)” sponsored under Nano Mission Programme of Department of Science & Technology (DST) Government of India. The details of the positions are as below:

Concordia International is the result of the acquisition by Concordia Healthcare Corp (now Concordia International Corp) of the AMCo group on 21 October 2015.The combined businesses are highly complementary to each other, with well established product portfolios, and provide a strong platform for future growth through acquisitions in line with its strategy to build a truly global pharmaceutical company.

Post : Regulatory Affairs Executive