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October 2015

 

 

academics

 

Clinical research courses

Vacancy for B.Pharm as Procurement Officer - Palghar at Bliss GVS Pharma

Bliss GVS is a fast-growing Pharmaceutical Company with a proven track record of developing, manufacturing and marketing high quality pharmaceutical formulations at affordable prices for the global market. We are a public limited company listed on India’s National Stock Exchange and Bombay Stock Exchange with more than three decades of industry expertise. We are among the world leaders in Suppositories and Pessaries dosage forms with one of the largest portfolios in this segment. Our thirty years of experience in suppositories manufacturing has resulted in developing an extensive product offering in suppositories and pessaries across various therapeutic categories (see here). We follow European GMP Standards for manufacturing suppositories.

Post: Procurement Officer - Palghar

Recruitment for Pharmacist in Cantonment Board Jalandhar

Cantonment Board Jalandhar is inviting applications for Recruitment to the post of Pharmacist, as per the details given below.

Post: Pharmacist

Work as Product Manager [International] - Lifeon Labs [Cosmetics] in Bliss GVS Pharma

Bliss GVS is a fast-growing Pharmaceutical Company with a proven track record of developing, manufacturing and marketing high quality pharmaceutical formulations at affordable prices for the global market. We are a public limited company listed on India’s National Stock Exchange and Bombay Stock Exchange with more than three decades of industry expertise. We are among the world leaders in Suppositories and Pessaries dosage forms with one of the largest portfolios in this segment. Our thirty years of experience in suppositories manufacturing has resulted in developing an extensive product offering in suppositories and pessaries across various therapeutic categories (see here). We follow European GMP Standards for manufacturing suppositories.

Post: Product Manager [International] - Lifeon Labs [Cosmetics]

Walk in for Junior Research Fellowship in University and Institute of Advanced Research

Walk in interview for the Junior Research Fellow (JRF) position in Department of Chemistry at the University and Institute of Advanced Research, GANDHINAGAR

Post: One Junior Research Fellowship (JRF)

DBT sponsored 5th ANNUAL INTERNATIONAL CONVENTION OF ASSOCIATION OF PHARMACY PROFESSIONALS THEME Redefining Pharmacy Education and Regulations for Translational Drug Research in India at Anna University

APP is a professional organization (Registered under Society Registration Act, Govt. of India) consisting of more than 600 pharmacy professionals from all over India and abroad. APP is willing and committed to serve pharmacy profession in all possible aspects, promote pharmaceutical education and research, recognize and honor experts, create awareness, continuing education, industry academic relationship and overall welfare of the pharma community through various professional activities.

DETERMINATION OF ANTIBACTERIAL, ANTIFUNGAL AND CYTOTOXIC ACTIVITIES OF N-HEXANE, CHLOROFORM AND ETHYL ACETATE EXTRACTS OF MOMORDICA CHARANTIA LEAVES

{ DOWNLOAD AS PDF }

ABOUT AUTHOR:
Israt Jahan Bulbul
Department of Pharmacy,
Southeast University Banani, Dhaka, Bangladesh
israt_jahanb872@yahoo.com

ABSTRACT
A study was conducted to determine the antibacterial and antifungal activitieswith minimum inhibitory concentration and cytotoxic activity of Momordica charantia (Family: Cucurbitaceae) leaves. In our present study, the antimicroial activity of n-hexane, chloroform and ethyl acetate fractions of the plant were investigated against a number of pathogenic Gram-positive (Bacillus megaterium, Bacillus subtilis, Staphylococcus aureus and Sarcina lutea), Gram- negative (Salmonella paratyphi, Salmonella typhi, Vibrio parahaemolyticus, Vibrio mimicus, Escherichia coli, Shigella dysenteriae, Shigella boydii and Pseudomonas aeruginosa) bacteria and three funguses (Candida albicans, Aspergillus niger and Saccharomyces cerevesiae). Here the zones of inhibitions for the test samples (500 µg /disc) werecompared with that of reference standard (30 µg /disc) in determining antimicrobial activity. All the extracts showed significant antibacterial and antifungal activities against all the pathogenic bacteria except A. niger. The highest sensitivity for n-hexane, chloroform and ethyl acetate fractionswas against gram positive bacteria B.cereus. Almost all the gram positive, gram negative bacteria and fungus were inhibited by ethyl acetate extract and showed better activity compared to n-hexane and chloroform extracts. All the three fractions were tested as antifungal against C. albicans and S. cerevesiae. They showed moderate activity against C. albicans whereas a very good activity against S. cerevesiae. But A. niger was not sensitive to the experimental extracts.Minimum inhibitory concentration (MIC) that is the lowest concentration at which the test sample shows its highest activity against microorganisms was tested by serial dilution method. The MIC for n-Hexane and chloroform extracts was against B. cereus (64 µg /ml).  The ethyl acetate extract exhibited antibacterial activity with MIC of 64 µg /ml against S. aureus, S. luteae, S. boydii, S. dysentereae and V. mimicus. The Brine shrimp lethality bioassay method was used to determine the cytotoxic activity and vincristine sulphate was used as positive control. The LC50 values of standard vincristine sulphate, n-hexane, chloroform and ethyl acetate extract were 10.18 µg /ml, 24.71 µg /ml, 19.02 µg /ml and 30.38 µg/ml respectively which indicate the presence of bioactive compounds present in the plant extracts are promisingly cytotoxic.

Mammograms - everything you need to know

What is a mammogram?
A mammogram is an x-ray picture of the breast.
Mammograms can be used to check for breast cancer in women who have no signs or symptoms of the disease. This type of mammogram is called a screening mammogram. Screening mammograms usually involve two x-ray pictures, or images, of each breast. The x-ray images make it possible to detect tumors that cannot be felt. Screening mammograms can also find microcalcifications (tiny deposits of calcium) that sometimes indicate the presence of breast cancer.

One of the world’s most in-demand anaesthetics can now be produced on the spot, thanks to the thermos-flask sized device that recently won Flinders University inventor Professor Colin Raston an Ig Nobel prize.

Two days seminar on Phamracovigilance in Ayurveda sponsored by ICMR, AYUSH AND RGUHS was organized by Acharya &   B M Reddy College of Pharmacy, Bengaluru in association with IPA, Karnataka State branch, Peenya branch and Education Division.

On 19th August 2015 morning the program was inaugurated by, Padma Bhushan Dr. Belle Monappa Hegde, retired Vice chancellor, Manipal Academy of Higher Education. Dr Divakar Goli, Editor- IJPS and Principal of Acharya & B M Reddy College of Pharmacy, Bengaluru. Prof. Brahmam Head QUICAI,  Acharya Institute, Bengaluru. The welcome speech was delivered by Dr Divakar Goli. Prof. H. R. Ambujakshi, Organizing Secretary of the seminar given the introduction about the seminar. Dr. B.M. Hegde delivered stimulating, enthralling and interactive lecture. He spoke about the drastic change required in present medical practice.

First session was Dr. Ramananda S. Nadig, MD, Head – Medical Services & Clinical Development, The Himalaya Drug Company, Bengaluru. He has enlightened about the severity of the ADR’s problems, Serous Adverse Events, Pharmacovigilance regulations and scope of pharmacoviglance in India. He concluded with take home message of “Avoid ADR, stay vigilant, inform about ADR” Dr. Lalitha B.R, Professor of Government Ayurveda Medical College, Bengaluru was the speaker of the 2nd session. She has enlightened about Ayurvedic Perspective and Utility “and highlighted about the Challenges in introducing pharmacovigilance. Third session was by Dr Chaithra S. Hebbar, Associate Professor, SDM College of Ayurveda, Udupi, She spoke about the seven forts of protection surrounding Ayurveda medicine prescription. She made delegates to understand about the wise use of ancient and modern therapeutic skills in a complementary manner should build a Holistic, personalized, safe and effective medicines for the demanding community.

On 20th August 2015 the morning began with session on Herbal Nutraceuticals and Pharmacovifilance: Global scenario by Dr. H.N. Shivaprasad, Director, Prakruthi Products Pvt. Ltd., He said that current supplement industry safety practices are inadequate. According his opinion the industry needs to take aggressive steps to demonstrate a safety focus– self-regulation.


The second session was on Pharmacovigilance of indigenous drugs; Need Envisaged by Dr Pralhad S Patki Professor of Pharmacology, International Medical School. Bengaluru. He discussed about epidemiology and classification of ADRs with reference to indigenous drugs and described about basic methods to detect, evaluate and document ADRS. The third session was honored by the lecture of Dr. S.L. Hoti, Scientist and Deputy Director, Regional Medical Research Centre (ICMR), Belgaum. He explained about the needs of Pharmacovigilance and challenges in monitoring the safety of herbal medicines. This was followed by Valedictory Function. The chief guests were Dr. S.L. Hoti, and Dr. Shivakumar. T, DivisionalDrug Controller of Ayurveda, Government of Karnataka, Bengaluru. Organizing Secretary H.R. Ambujakshi, concluded the seminar by brief a summary and Dr. Rajesh Asst. Prof of Acharya & B.M. Reddy College of pharmacy  proposed the vote of grateful thanks to all those who had helped to make the seminar  a success.

Dignitaries Present in Inauguration Ceremony from Left to Right: Prof. Brahmam, Dr Divakar Goli,  Dr. Belle Monappa Hegde, Prof. H. R. Ambujakshi,


Felicitation to Padma Bhushan Dr. Belle Monappa Hegde


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