December 2014

Origo Pharmaceuticals Pvt Ltd is a leading company offering a unique range of cosmeceutical products in the Skin Whitening , Anti-ageing and Hair-care segment to its customers across India and the Middle-East. Our products are manufactured at our state-of-art facility in Bangkok, Thailand. We also offer tailored dermato-cosmetics products (contract manufacturing services) for many of the leading dermatologists/cosmetologists in India.

Sir Ganga Ram Hospital is a 675-Beded multi-speciality state-of-the-art Hospital in India. It provides comprehensive Healthcare India services, and has acquired the status of a premier medical institution. It is the only hospital in the private sector that has maintained nearly 100% bed occupancy due to its reputation of providing the highest level of medical services to patients from Delhi and neighbouring states.

Anna University was established on 4th September 1978 as a unitary type of University. It offers higher education in Engineering, Technology and allied Sciences relevant to the current and projected needs of the society. Besides promoting research and disseminating knowledge gained therefrom, it fosters cooperation between the academic and industrial communities.The University was formed by bringing together and integrating two well-known technical institutions in the city of Madras.

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ABOUT AUTHORS:
Anuradha Sharma¹*, Vaibhav Walia², Monika Gahlawat^3
1Division of Pharma. Chemistry,² Division of Pharmacology,³ Division of Pharmaceutics,
G.V.M. College of Pharmacy,
Sonepat, Haryana, India
*anusarswat@gmail.com

ABSTRACT
Type 2 diabetes is one of the major life threatening diseases worldwide. These cases are progressing at an incremental rate every year and number of research works is going on to control the disease by targeting its enzymes or proteins. In modern drug designing, molecular docking is routinely used for understanding drug receptor interaction. In the present study molecular docking were performed on a diverse set of N-(2-benzoylphenyl)-L-tyrosine derivatives that demonstrate antidiabetic activity by stimulating peroxisome proliferator activated receptor- γ. The docking program in Glide dock justifies the correlation between the experimental values and the values derived computationally. Therefore, the dock analysis performed in Glide dock suggests the importance of evaluating the prediction accuracy of scoring functions adopted in various docking program.

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