November 2014

Soranus Lifesciences is an innovative leading, vertically integrated pharmaceutical formulation company that discovers, develops, manufactures and markets a broad range of healthcare products. Headquartered in the city of Ahmedabad in India, The Company has dedicated research and development department well equipped with the latest equipments and supported by a large pool, of scientists who continuously work towards new pharma products.

Soranus Lifesciences, Our Corporate Group is associated with other business like leading Broking House of India, having vast exposure to Pharmaceutical Distribution since last 25 years along with chains of Retail Medical Stores and Infrastructure.  Our basic philosophy is to create care with lot of values.

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ABOUT AUTHOR:
Madhusudan P Dabhole
Group Manager - BioProcess,
Richcore Life Sciences Ltd, Bangalore, Karnataka, India.
madhav888@rediffmail.com

ABSTRACT
The scale up of recombinant proteins involves a multi- dynamic strategic approach to achieve maximum output consistently. Various parameters during the fermentation will limit the synthesis of desired protein, which otherwise can be produced with ease in case of classical fermentation. In order to synthesis the protein, it is very important to understand the process at laboratory scale – both from scale up point of view and productivity improvement at large scale. Some of this parameters and scale up parameters are discussed below in this review.

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