October 2014

National Institute of Malaria Research (NIMR) was established in 1977 as 'Malaria Research Centre', which was renamed as 'National Institute of Malaria Research' in November 2005. NIMR is one of the institutes of the Indian Council of Medical Research (an autonomous body under Department of Health Research, Ministry of Health & Family Welfare, Govt. of India). The primary task of the Institute is to find short term as well as long term solutions to the problems of malaria through basic, applied and operational field research. The Institute also plays a key role in man power resource development through trainings/workshops and transfer of technology.

Following position need to be filled up on purely temporary and contract basis, co-terminus with the projects.

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ABOUT AUTHORS:
Duvvuru Ashok Kumar¹*, Languluri Reddenna^2
1Department of Pharm-D, P. Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India
²Department of Pharmacy Practice, Rajiv Gandhi Institute of Medical Sciences, Kadapa, Andhra Pradesh, India
ashok.alex11@gmail.com

ABSTRACT
MS is the most common inflammatory-demyelinating disease of the central nervous system (CNS). MS is estimated to affect 400,000 persons in the United States and 2 million people worldwide. Women are affected twice as frequently as men, between the ages of 20 and 40. The etiology of MS is still unknown, but according to current data the disease develops in genetically susceptible individuals and may require additional environmental triggers. In this paper, we present the insight on simple cure for multiple sclerosis.

CEPS established under the aegis of GGSIP University is engaged in research/teaching in Pharmaceutical Chemistry/Pharmacology/Microbiology & Bioethics. CEPS is looking for meritorious young researchers for pursuing research in the area of Pharmaceutical Chemistry, Detection, Isolation, Structural Elucidation & Biological Screening.

The University Institute of Pharmaceutical Sciences of the Panjab University is a premier institution of Pharmaceutical Education and Research in the country. The institute has covered a long and glorious journey of 76 years starting from Lahore in 1944 and finally settling to the present campus in Chandigarh at the foothills of Himachal. In its travelogue, the institute crossed multiple milestones and continue to head ahead towards the well-defined goals. The elevation of the status from department to the level of an institute i.e. University Institute of Pharmaceutical Sciences in 1994, and hosting of Indian Pharmaceutical Congress in the same year, two presidential honors of the Indian Pharmaceutical Congresses to its faculty members, a special recognition by the UGC by granting SAP in 1993 and COSIST in 1981 establishment of ICMR Advanced Centre for standardization of Drugs of Indian System of Medicine are some of the major hallmarks on the path treaded so far.

Post: Research Fellow/Programme Assistant

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ABOUT AUTHORS
Balay Ragini*, A.Pavani, R.Raja Reddy
Malla Reddy Pharmacy College,
Maisammaguda(via-hakimpet), Secunderabad, Telengana. india
ragini.balay@gmail.com

ABSTRACT
Cefuroxime Axetil is a second generation antibacterial belongs to Cephalosporin Group. The drug undergoes rapid metabolism in intestinal mucosa due to change in pH Environment and hence has decreased oral bioavailability. The aim of present investigation is to increase the gastric residence time by preparing gastroretentive tablets here by improving bioavailability of Cefuroxime Axetil. A simple UV spectrophotometric method has been employed for the estimation of Cefuroxime Axetil at 281 nm. A floating drug delivery system (FDDS) was developed using gas-forming agents, like sodium bicarbonate, sodium alginate and hydrocolloids like hydroxyl propyl methyl cellulose (HPMC) and guggul. The prepared tablets were evaluated in terms of their precompression parameters, physical characteristics, In vitro release, buoyancy lag-time and swelling index. The formulations were optimized for the different grades of HPMC, and its concentrations and combinations. The results of the In vitro release studies showed that the optimized formulation F3 could sustain drug release of 92% and remain buoyant for 10h. The optimized formulation was subjected to various kinetic release investigations and it was found that the mechanism of drug release was predominately Higuhci with non fickian diffusion. Finally the tablets formulations found to be economical and may overcome the draw backs associated with the drug during its absorption.

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