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December 2013

 

 

academics

 

Clinical research courses

PYRAZOLE AND ITS BIOLOGICAL ACTIVITY

ABOUT AUTHORS:
Vishwanadham Yerragunta*1, Duggi.Suman1, Kumara swamy1, V.Anusha1, Pratima Patil1, M. Naresh2
Department of Pharmaceutical Chemistry,
1Malla Reddy College of Pharmacy, Maisammaguda, Secunderabad-500014, A.P.
2Bharath Institute of Technology Pharmacy-Ibrahimpatnam, AP.
*vishwanadham.y@gmail.com

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ABSTRACT:
The aim of this review is to provide an overview of diverse pharmacological activities of pyrazole moiety. Pyrazole are well known and important nitrogen containing 5-membered heterocyclic compounds and various methods have been worked out for their synthesis. Pyrazole chemically known as 1, 2-diazole has become a popular topic due to its manifold uses. Numerous pyrazole derivatives have been found to possess a broad spectrum of biological activities, which stimulated the research activity in this field. Pyrazoles and its derivatives represent one of the most active classes of compounds, which possess wide range of biological activities like anti-bacterial, anti-convulsant, analgesic, anti-microbial, anti-inflammatory, ant diabetic, sedative anti-rheumatic, anticancer, and anti-tubercular activities. The purpose of this review was to collate literature work reported by researchers on pyrazole for their various pharmacological activities and also reported recent efforts made on this moiety.

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Jyotirmoyee Patnaik
Kanak Manjari Institute of pharmaceutical Sciences.
Rourkela, Orissa
patnaik.jyotirmoyee@gmail.com

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