October 2013

Largest producer of Ayurveda medicines in public sector in India, One among the few Public Sector companies, consistently making profit and paying dividend to Government of Kerala since 1999. Supplies medicine to Government of Kerala for the distribution to common man through ISM Dept. A GMP and ISO 9001-2008 certified company. Produces 450 Ayurvedic formulations - both classical and proprietary. Sole supplier of medicines to Government Ayurveda Hospitals and proprietary.

The history of the IIT system dates back to 1946 when a committee was set up by Hon'ble Sir Jogendra Singh, Member of the Viceroy's Executive Council, Department of Education, Health and Agriculture to consider the setting up of Higher Technical Institutions for post war industrial development in India.

ABOUT AUTHORS:
Sandeep Kumar Patro*, M.Jhansi, Dr.A.M.S.Sudhakar Babu, Sk.Asief, P.Ramesh Babu
A.M.Reddy memorial college of pharmacy, Narasaraopet.
Sandeepkumarpatro2@gmail.com

ABSTRACT
Study of drug - excipient compatibility is an important process in development stage of dosage forms. Incompatibility between drugs and excipients alter drug stability and bioavailability &there by affect their safety and efficacy. Dosage form is a pharmaceutical drug delivery system, which is a combination of drug(s) and non-drug  components called as excipients. Drug is a chemical substance obtained from either natural, synthetic or semi synthetic source, which is used for the treatment, curing, prevention  or mitigation of a disease or disorder in human beings or animals Excipients are nondrug components which are serve specific purposes like shape, stability, solubility, elegance, palatability etc. of a dosage form. These are also called as adjuvants, additives or pharmaceutical aids. The evaluation of drug-excipient compatibility is therefore an essential aspect of any preformulation study. To evaluate the drug- excipient compatibility different techniques such as  Thermal analysis, Differential scanning  calorimetric (DSC) study, Infra red spectrophotometric study (IR), Isothermal stress testing (IST), High performance liquid chromatography (HPLC),Thin layer chromatography (TLC), Solution calorimetry  were adopted.

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Post: Associate Research Analyst - JREQ008858