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May 2013

 

 

academics

 

Clinical research courses

MICROSPHERE AS DRUG CARRIER: A REVIEW

ABOUT AUTHORS:
Madhuri D. Ghadage*1, Gajanan H. Banapure2
1Department of Pharmaceutics, SMBT College of Pharmacy, Dhamangaon, Nashik
2H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur Dhule

*maadhuri.ghadge@gmail.com

ABSTRACT
The controlled release of drugs in slow and sustained manner is one of the major challenges in drug delivery system. Targeting of drug to the particular site is an important aspect of drug delivery system. Carrier technology offers an intelligent approach for drug delivery by coupling the drug to a carrier particle such as microsphere which modulates the release and absorption characteristics of the drug. These delivery systems offer numerous advantages over the conventional dosage forms including improved efficacy, reduced toxicity, and improved patient compliance. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs. In future microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, genetic materials, targeted and effective drug delivery. The current aim of this review is to study various aspects of the microparticulates drug delivery system including method of formulation, evaluation & characterization.

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