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February 2013

 

 

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AN OVERVIEW OF MIRACULOUS VEGETABLE DRUG - DIOSCOREA (YAM)

ABOUT AUTHORS:
Prashanta kr. Deb1, Tejendra Bhakta2*,
1Dept. of Pharmacy, Tripura University; Suryamaninagar –799 022, Agartala, Tripura (w).
2Regional Institute of Pharmaceutical Science & Technology, Abhoynagar – 799005, Agartala, Tripura (w).

shaandeb2010@gmail.com

INTRODUCTION
Dioscorea is a slender twining annual herbs distributed throughout the tropical and subtropical region of the world. Dioscorea is a fascinating plant with many uses in the history of the development of modern pharmacy. The number of species is quite overwhelming (over 600) and the Ethno-botanical uses are most interesting. Dioscorea is a genus of over 600 species of flowering plants in the family Dioscoreaceae. They are tuberous herbaceous perennial climber, growing to 2–12 m or more tall. The leaves are spirally arranged, mostly broad heart-shaped. The flowers are individually inconspicuous, greenish-yellow, with six petals; they are mostly dioecious, with separate male and female plants, though a few species are monoecious, with male and female flowers on the same plant. The fruit is a capsule in most species, a soft berry in a few species. Several species, known as yams, are important agricultural crops in tropical regions, grown for their large tubers. Some species produces large cylindrical tubers penetrating deep into the ground, while other varieties produce small or large tubers close to the soil surface. Sometimes 1-2 tubers are produce at the base of the plant while in the other cases cluster of tubers are observed. Many of these are toxic when fresh, but can be detoxified and eaten, and are particularly important in parts of Africa, and Asia.

EVALUATION OF ANTIDOTE ACTIVITY OF LEAVES OF MUSA SAPIENTUM LINN. ON RATS

About Authors:
Vishnu Dev 1*, Rajiv saxena 2
1 Truba Institute of pharmacy, Bhopal.
2 Assoc. Professor, Truba Institute of pharmacy, Bhopal
*vishnudev2007@rediffmail.com

Abstract
The present study was designed to investigate the anti-dote activity of the methanolic and aqueous extract of musa sapientum. The extract was evaluated by physical and serum biochemical parameters as TC and TG. Anti-dote activity of both extract was determined by acute and chronic codeine poisoning,
Acute opioid intoxication and overdose are common causes of presentation to emergency departments. Although naloxone, a pure opioid antagonist, has been available for many years, there is still confusion over the appropriate dose and route of administration. This article looks at the reasons for this uncertainty and undertakes a literature review from which a treatment algorithm is presented.
The anti-dote activity of musa sapientum leaves against codeine induced acute and chronic poisoning was studied in Wistar albino rats. The various fractions of the leaf extract were administered orally (200 mg/kg) simultaneously with codeine (32m g/kg) for 5-10 days. At the end of the experiment, levels of triglycerides, total cholesterol content were measured. Administration of codeine produced a CNS depressant activity and causes poisioning. There was a significant increase in total cholesterol and triglycerides when compared to normal control. physical observation indicated that simultaneous administration of the fractions delayed the onset of toxicity. All the fractions prevented the poisoning damage caused codeine overdose. The leaves of musa sapientum protected the CNS against codeine damage which may be due to its antagonist activity of codeine.

Indian Institute of Chemical Technology invites multiple vacancies - Walk in | 58 Posts

Indian Institute of Chemical Technology, Hyderabad is a premier R&D Institute in India. The Institute had its origin as the Central Laboratories for Scientific & Industrial Research (CLSIR), established in 1944 by the then Government of Hyderabad State. After integration of Hyderabad State with the Indian Union, the laboratory expanded with its growing activities. The main building was formally opened by Pandit Jawaharlal Nehru, the then Prime Minister of India on January 2, 1954.

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REVIEW ON SUPER BUG (NDM-1)

About Author:
Kambham Venkateswarlu
Final Year Graduate Student
Sri Lakshmi Narasimha College of Pharmacy,
Palluru, Chittoor-517132, Andhra Pradesh, India.
k.v.reddy9441701016@gmail.com

ABSTRACT:
The term superbug is a nonspecific word that is used to describe any microorganism that is resistant to at least one or more commonly used antibiotics. Some authors restrict its use to microorganisms resistant to two or more antibiotics.

The most common bacteria described as superbug are the following:
* MRSA (Staphylococcus aureus strains resistant to multiple antibiotics)
*  VRE (Enterococcus species resistant to vancomycin)
*  PRSP (Streptococcus pneumonia strains resistant to penicillin)
*  ESBLs (Escherichia coli and other Gram-negative bacteria resistant to antibiotics such as cephalosporins and monobactams)

Emerging superbugs may be multiple drug resistant Clostridium difficile, VRSA (vancomycin resistant S.sureus) and NDM Escherichia coli (New Delhi metallo-beta-lactamase resistant E.coli).

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A CURRENT REVIEW ON ANTIVIRAL DRUGS

About Authors:
Mayure.Vijay Kumar*1, Mayure.Ashok2, Athiya Mohammadi1,  C.P.Meher1
Department of pharmaceutical chemistry
1Maheshwara College of Pharmacy, Chitkul (V), Isnapur “X” Road, Patancheru, Hyderabad,
2Gokaraju Rangaraju College of pharmacy, Hyderabad.

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