Pharmapedia

In the new study, researchers modified DNA from a bacteriophage or “phage,” a type of virus that infects and replicates inside of bacteria. Then, the research team put the DNA inside Pseudomonas aeruginosa (P. aeruginosa), a deadly bacterium that is also highly resistant to antibiotics. Once inside the bacterium, the DNA bypassed the pathogen’s defense mechanisms to assemble into virions, which sliced through the bacterium’s cell to kill it.

Most patients with Type 2 diabetes will end up needing to add a second-line medication after metformin - the go-to primary drug for glucose management to control their blood sugar levels. But adherence to these second-line drugs can be hit or miss, reports a new Northwestern Medicine study.

ABOUT AUTHOR
Dr. R. S. Thakur
Former Secretary, Pharmacy Council of India.
Email : drramsthakur@gmail.com

Insulin icodec, a once-weekly basal injection to treat type 1 diabetes, has the potential to be as effective in managing the condition as daily basal insulin treatments, according to research from the University of Surrey. The results of the year-long phase 3 clinical trial could revolutionise the future of diabetes care and help millions of people better manage their condition.

The Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen) announced today promising data from a Phase 2a human challenge study evaluating JNJ-1802, a first-in-class oral antiviral in development for the prevention of dengue. The data showed that the compound induced antiviral activity against dengue (DENV-3) in humans, compared to placebo, and is safe and well-tolerated. The data were announced at the American Society of Tropical Medicine & Hygiene Annual Meeting in Chicago, Illinois.

Vinay Kumar Singh.  
Head-Formulation
Kumar Organic Products Research Centre Pvt. Ltd.,
Bengaluru
Email : formulation_krc@kopresearchcentre.net

Learn all Career opportunity for Indian Phamacists in Canada with smart, energetic and experienced pharma experts.

Canada has approximately 42,500 licensed pharmacists working in more than 10,000 pharmacies. Of those, about 70% work in community pharmacies, 15% work in hospitals, and 15% work in other settings such as the pharmaceutical industry, governments, associations, colleges and universities. 

Formulation chemistry is the branch of manufacturing that deals with substances that don't react with each other, but contribute to the final product in some way. For example, an Anti-ageing Cream contains Bakuchiol, Emulsifiers, Emollients, Humectant, Preservative, Fragrance, etc.

Ceftazidime in combination with avibactam is a last-line antibiotic, to be used as a targeted therapy for certain carbapenem-resistant Gram-negative infections and not to be used as an empirical therapy. But the antibiotic recently lost its exclusivity and became a generic drug in India. And scientists from ICMR are foreseeing certain potential adverse implications of introducing generic versions of ceftazidime/avibactam into the Indian market.