Anti-Adrenergic Drugs
Anti-adrenergic agents are those which act on adrenergic receptors and block their activity. It reduces sympathetic out flow and antagonised them.
Table of Content |
α blockers:
These are agents which antagonised α receptors and decreases sympathetic activity.
Non equilibrium type, Phenoxybenzamine.
Equilibrium type,
Non selective: ergotamine, ergotoxine, tolazoline, chlorpromazine.
Selective:
α1 selective: prazosin, doxazocin.
α2 selective: yohimbine.
β Blockers:
These are the agents which block the β-receptors present in the body.
β-receptor antagonists are classified as, Nonselective and Selective.
Non selective (β1 & β2):
Membrane stabilizing activity without intrinsic sympathomimetic activity: Propranolol, Timolol, Sotalol.
Membrane stabilizing activity with intrinsic sympathomimetic activity: Pindolol.
With additional α blocking activity: Labetalol, Carvedilol.
Selective:
β1 selective: Atenolol, Metoprolol, Acebutolol, Esmolol.
β2 selective: Butoxamine.