NOV 2014 ARTICLE LIST >>
PharmaTutor (November- 2014)
ISSN: 2347 - 7881
(Volume 2, Issue 11)
Received On: 27/09/2014; Accepted On: 01/10/2014; Published On: 01/11/2014
AUTHORS: Priyanka T*, Giri raja sekhar D, Lekhanth A, Revanth.A
Department of Pharmacy Practice,
Annamacharya College of Pharmacy
Rajampet, Andhra Pradesh, India
priyankat283@gmail.com
ABSTRACT:
Hair loss in women is twice more distressing in women when compared to men. The most common cause of hair loss in women is Female Androgenic Alopecia (FAGA) which shows Ludwig, Christmas tree, Hamilton pattern. Androgenic alopecia is due to the increased activity of 5α-reductase in the hair follicles which results in the gradual transformation of large, terminal follicles to small, miniaturized follicles. Finasteride is a 5α-reductase II enzyme which inhibits the conversion of testosterone to dihydro testosterone and is effectively used in the management of the male pattern androgenic alopecia with a dose of 1mg/day but this article mainly reviews the use of Finasteride in the female androgenic alopecia. Studies so far reported increased scalp hair counts, hair density, hair regrowth both by the patient assessment and photographs by the blinded expert panel. Relevant literatures were chosen to determine the efficacy of Finasteride in the treatment of female Androgenic Alopecia.
How to cite this article: T Priyanka, GR sekhar, A Lekhanth; Finasteride in the Treatment of Female Androgenic Alopecia; PharmaTutor; 2014; 2(11); 10-15
[ABSTRACT WITH CITATION] [VIEW AS HTML]
REFERENCES:
1. British Columbia poison and drug information centre. Available at dpic.org/article/professional/finasteride-hair-loss-womenaccessed on (25/08/2014).
2. Olga Boychenko, Robert M. Bernstein, Eric S. Schweiger. Finasteride in the Treatment of Female Pattern (Androgenic) Alopecia: A Case Report and Review of the Literature.cutaneous medicine for the practitioner.2012;90:73-76.
3. Vera H Price. Androgenetic Alopecia in Women. Journal of Investigative Dermatology Symposium Proceedings. 2003;8: 24–27.
4. Ingrid Herskovitz, Antonella Tosti. Female Pattern Hair Loss. International Journal of Endocrinology and Metabolism. 2013 Oct; 11(4): e9860.1-8
5. Quan Q Dinh, Rodney Sinclair. Female pattern hair loss: Current treatment concepts. Clinical Interventions in Aging. 2007; 2(2): 189–199.
6. Blumeyer A, Tosti A, Messenger A, Reygagne P, Del Marmol V, Spuls PI, et al. Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men. Journal of the German Society of Dermatology. 2011;9 Suppl 6:S1-57
7. Price VH, Roberts JL, Hordinsky M, et al. Lack of effi¬cacy of finasteride in postmenopausal women with andro¬genetic alopecia. Journal of the American Academy of Dermatology. 2000;43(5, pt 1):768-776.
8. Camacho F. Hirsutismo. enfoque clinico terapéutico. Actualizaciones Terapeuticas Dermatologicas 2001;24:190-206.
9. Shum KW, Cullen DR, Messenger AG. Hair loss in women with hyperandrogenism: four cases responding to finaster-ide. Journal of the American Academy of Dermatology. 2002;47:733-739.
10. Thai KE, Sinclair RD. Finasteride for female androgenetic alopecia. British Journal of Dermatology. 2002; 147: 812-813.
11. Trüeb RM; Swiss Trichology Study Group. Finaster-ide treatment of patterned hair loss in normoandro¬genic postmenopausal women. Dermatology. 2004;209:202-207.
12. Valsecchi R, Leghissa P, Riva M. Female pattern alopecia treated by finasteride: a case forward. Acta Dermato Venerologica. 2004; 84: 488-489.
13. Iorizzo M, Vincenzi C, Voudouris S, et al. Finasteride treatment of female pattern hair loss. Archives of Dermatology. 2006;142:298-302.
14. Hong JB, Chiu HC, Chan JY, et al. A woman with iat¬rogenic alopecia responding to finasteride [published online ahead of print January 30, 2007]. British Journal of Dermatology. 2007;156:754-755.
15. Kohler C, Tschumi K, Bodmer C, Schneiter M, Birkhauser M. Effect of finasteride 5 mg (Proscar®) on acne and alopecia in female patients with normal serum levels of free testosterone. Gynecology Endocrinology. 2007; 23: 142-145.
16. R Oliveira-Soares, J Maia e Silva, M Peres Correia, Marisa C André. Finasteride 5 mg/day Treatment of Patterned Hair Loss in Normo-androgenetic Postmenopausal Women. International Journal of Trichology. 2013; 5(1): 22–25.
17. Carmina E, Lobo RA. Treatament of hyperandrogenic aloipecia in women. Fertility and Sterility. 2003; 79: 91-95.
.png)
